Long-term treatment of a child with congenital adrenal hyperplasia

Background Congenital adrenal hyperplasia (CAH) is one of the autosomal recessive disorder caused by an enzyme deficiency or defect in one of five enzymatic steps which are required for the biosynthesis of adrenal steroid. CAH could be a medical and social crisis, and especially in South Sumatera, Indonesia it is also associated with cultural problems. Natural history of CAH without treatment can cause death due to loss of salt crisis unless it can be detected and treated early.